As the game unfolds, Rupert and Emma find themselves guided by cryptic clues left by a shady stranger, calling on them to face a host of challenges and obstacles in order to find the cure before time runs out. The distraught parents immediately set out to save their daughter's sight and embark on a worldwide search for a mythical Golden Jewel Board, rumored to hold the antidote that will cure her. While playing with a mysterious jewel board, Rupert and Emma's daughter Natalie pops open a secret compartment that releases spores into the air, causing her vision to fade. In Jewel Quest 3, the third installment in the highly popular Match 3 game, Rupert and Emma have settled down and opened a museum to display the many artifacts they have collected over the years.